In the article “A semi-synthetic organism with an expanded genetic alphabet,” published in Nature, researchers Denis A. Malyshev, Kirandeep Dhami, Thomas Lavergne, Tingjian Chen, Nan Dai, Jeremy M. Foster, Ivan R. Corrêa, and Floyd E. Romesberg of The Scripps Research Institute in La Jolla, California, demonstrate successful laboratory replication of artificial DNA, using not only the natural CGTA bases but also artificial XY bases (D5SICS and dNaM). This is the first true artificial life and proof that life is possible beyond the path taken by Darwinian evolution.
